Late Night with Seth Meyers Season 5 Ellen Pompeo, John Leguizamo, Jhené Aiko Season 5, episode 21 Ellen Pompeo, John Leguizamo, Jhené Aiko November 7, 2017 45 min Seth welcomes Ellen Pompeo, John Leguizamo and Jhené Aiko. Previous episode Rosie O’Donnell, David France Next episode John Lithgow, Jonathan Groff, Michael Lewis