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Episode 1
Fallen
October 3, 2010, 43 min
The CSI's must catch a madman causing havoc all over Miami and the team has to mourn one of their own.
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Episode 2
Sudden Death
October 10, 2010, 42 min
When a woman is murdered at an exclusive club, Horatio must search through an elite guest list to find the killer.
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Episode 3
See No Evil
October 17, 2010, 43 min
When a girl is kidnapped, the only witness is a blind man who heard the abduction.
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Episode 4
Manhunt
October 24, 2010, 42 min
When the man who killed Horatio's wife breaks out of prison and goes on a rampage, the team tries to determine what he is after.
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Episode 5
Sleepless in Miami
October 31, 2010, 44 min
When a man claims to have dreamed of a murder before it happened, Horatio and Natalia go under cover to investigate him.
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Episode 6
Reality Kills
November 7, 2010, 43 min
When a reality TV star is murdered, the CSIs investigate the show's cast, the obsessed fans and the stars' hidden pasts.
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Episode 7
On the Hook
November 21, 2010, 44 min
The team must figure out why a fisherman is being targeted and keep him from being killed.
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Episode 8
Happy Birthday
December 5, 2010, 43 min
On the 200th episode Horatio must find an attacker and save a pregnant woman and hope he has an idea as to why she was attacked.
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Episode 9
Blood Sugar
December 12, 2010, 42 min
After an explosion at a sugar refinery information about an employee an comes to light.
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Episode 10
Match Made in Hell
January 2, 2011, 42 min
When the investigation of a dead millionaire leads the CSIs to an elite dating service, Ryan poses as a wealthy businessman to expose the matchmaker's lies.
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Episode 11
F-T-F
January 9, 2011, 43 min
After a fire hydrant washes away evidence, the team must recreate a bizarre double murder.
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Episode 12
Wheels Up
January 16, 2011, 43 min
The team investigates a murder at a roller derby match.
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Episode 13
Last Stand
February 20, 2011, 44 min
Memmo makes a return, bringing chaos to Miami and pitting him against Horatio in a final showdown.
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Episode 14
Stoned Cold
February 27, 2011, 44 min
When a high school bully dies as a result of a stoning, the CSIs have to find out which nerd is responsible.
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Episode 15
Blood Lust
March 6, 2011, 42 min
The team hunt for a serial killer before he can take another victim - who may be one of the team.
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Episode 16
Hunting Ground
March 13, 2011, 42 min
The CSIs uncover an exclusive hunting club where the prey is human.
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Episode 17
Special Delivery
March 20, 2011, 44 min
When a delivery truck driver and a housewife on his route are murdered, the CSIs try to find their connection.
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Episode 18
About Face
March 27, 2011, 42 min
An escaped prisoner takes Natalia hostage and tells her a shocking secret about his crimes.
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Episode 19
Caged
April 10, 2011, 42 min
Horatio must protect a fighter from his brother who escaped prison.
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Episode 20
Paint It Black
April 17, 2011, 44 min
When the CSIs find a co-ed dead in a hot tub, they investigate a case marked by jealousy, psychosis and college roommates.
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Episode 21
G.O.
May 1, 2011, 41 min
When Horatio chases down a mysterious murder suspect who claims he was framed, he discovers an elaborate charade.
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Episode 22
Mayday
May 8, 2011, 44 min
In the season finale, Horatio must capture an escapee again when their transport plane crashes. And the team was shocked to discover that the fugitive has planned more than that.